Human Genome

The CMB Faculty in this research area study how gene expression is regulated at steps including transcription, localization, translation, modification and decay.  They use approaches such as next generation sequencing, live and fixed cell imaging, and digital PCR  to assess gene expression.

Faculty

Sarah  Swygert
Assistant Professor (Biochemistry and Molecular Biology)
We use high resolution genomics and biochemical/biophysical assays to uncover the roles of 3D chromatin structures in quiescent cells.

Tai MontgomeryDevin O’Connor
Assistant Professor (Biology)

Links plant development with the tools to engineer it with gene editing.

Debbie GarrityDeborah N. Garrity
Professor (Biology)
Molecular genetic approaches to gastrulation and organogenesis (especially heart development) in zebrafish.
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Tom SantangeloTom Santangelo
Professor (Biochemistry and Molecular Biology)
Mechanisms and regulation of archaeal transcription and RNA editing.
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Ashok Prasad
Professor (Chemical & Biological Engineering)

Mathematical and computational modeling of signal transduction, gene transcription and stochastic processes in biology.

​Cris Argueso​Cris Argueso
Associate Professor (Agricultural Biology)

Molecular mechanisms by which plant hormones regulate plant immunity and growth in the context of environmental change. Characterization of gene networks that regulate plant adaptation to stress.

 Jayne Aiken Jayne Aiken
Assistant Professor (Biomedical Sciences)

Integrates cell biology, bioengineering, and neuroscience to uncover the foundational cytoskeletal regulation guiding synaptic connectivity in health and disease.
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Ana Clara Bobadilla​
Assistant Professor (​Biomedical Sciences​)

Investigates the neurobiological mechanisms of relapse to drugs.  Specifically, she characterizes the specific ensembles of neurons linked to reward-seeking behavior.

​Jacob Cawley​​Jacob Cawley​
Assistant Professor (​Clinical Sciences​)

Cellular state regulation and developmental programs that inform cancer development and progression.

Karen Dobos
Professor (Microbiology, Immunology, and Pathology)
Her lab primarily uses biochemical approaches to study the physiology of microbial diseases. While she and her team are most known for their work in biomarker discovery and systems biology for Mycobacterium tuberculosis, they also actively work and collaborate to address novel questions around pathogen inactivation, vector-mycobacteria intersections, and pathogen/vector cryopreservation.

Tai MontgomeryTai Montgomery
Associate Professor (Biology)
Small non – coding RNAs and their roles in heterochromatin formation, transcriptional elongation, translation of mRNAs, and sorting of RNAs within a cell.

Erin NishimuraErin Nishimura
Assistant Professor (Biochemistry & Molecular Biology)
Regulation of gene expression during  C. elegans embryogenesis and how it impacts cell fate.

Anireddy ReddyAnireddy S.N. Reddy
Professor (Biology)
Signal transduction mechanisms; regulation of gene expression; crop improvement by genetic engineering.
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Carol Wilusz HeadshotCarol Wilusz
Professor (Microbiology, Immunology & Pathology)
Post – transcriptional control of gene expression in myotonic dystrophy and stem cells.

Jeffrey WiluszJeff Wilusz
Professor (Microbiology, Immunology & Pathology)
Interactions between viruses, viral RNAs and the cellular mRNA decay machinery.

Tingting Yao HeadshotTingting Yao
Associate Professor (Biochemistry & Molecular Biology)
Regulation of gene expression and chromatin dynamics by the ubiquitin – proteasome pathway.

Affiliate Faculty

Asa Ben-Hur
Professor (Computer Science)
Machine learning for predicting protein function and alternative splicing.

Jeff Hansen
Professor (Biochemistry & Molecular Biology)
Higher order chromatin structure and chromatin architectural proteins.

James Henriksen
Assistant Professor (Natural Resource Ecology Laboratory)

Brian Munsky
Assistant Professor (Chemical & Biological Engineering)
Integrating models & experiments to understand, predict and control stochastic processes such as gene expression

Lisa Schlein
Assistant Professor (Microbiology, Immunology & Pathology)

Laurie Stargell
Professor (Biochemistry & Molecular Biology)
RNA polymerase II transcription and chromatin context in S. cerevisiae.

Tim Stasevich
Assistant Professor (Biochemistry & Molecular Biology)
Live cell imaging of gene expression, especially post – translational modifications to chromatin

Coursework
  • BC 563 – Molecular Genetics
  • MIP 643 – RNA Biology
  • DSCI 510 – Linux as a computational platform
  • DSCI 511 – Genomics Data Analysis in Python
  • DSCI 512 – RNA-seq Data Analysis
  • MIP 565 / BZ 565 – Next Generation Sequencing Platforms & Libraries
  • MIP 611 – Advanced Microbiological Research Methods
Facilities & Resources
CMB Students

Ban Alkurdi (Swygert Lab)
2022 Cohort
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Rosi Danzman (Prasad Lab)
2021 Cohort
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Teagan Rockwood (Swygert Lab)
2023 Cohort
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Jared Van Blair (Santangelo Lab)
2025 Cohort
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Danielle Samson (O’Connor Lab)
2028 Cohort
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Alumni

Liam Elkins (MS 2025, Santangelo Lab) – Enzyme Engineer at National Laboratory of the Rockies
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Neha Ahuja (Garrity Lab)
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Josh Svendsen (Montgomery Lab)
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Sere Williams (MS 2019, Reddy Lab) – CMB PhD Student

Kristen Brown (PhD 2019, Montgomery Lab) – Data Science Fellow, Insight Data Science

Rasha Alnefaie (PhD 2018, Garrity Lab) – Lecturer, Albaha University

Aimee Jalkanen (PhD 2017, C. Wilusz Lab) – Clinical Research Manager, Merck

Annie Zhang Bargsten (PhD 2017, C. Wilusz Lab) – Scientific Support Specialist, Horizon Discovery

Mohammed Albaqami (PhD 2017, Reddy Lab) – Assistant Professor, Umm Al – Qura University