Human Genome

The CMB Faculty in this research area study how gene expression is regulated at steps including transcription, localization, translation, modification and decay.  They use approaches such as next generation sequencing, live and fixed cell imaging, and digital PCR  to assess gene expression.

Faculty

Cris ArguesoCris Argueso
Assistant Professor (Agricultural Biology)
Molecular mechanisms by which plant hormones regulate plant immunity and growth in the context of environmental change. Characterization of gene networks that regulate plant adaptation to stress.

Debbie GarrityDeborah N. Garrity
Professor (Biology)
Molecular genetic approaches to gastrulation and organogenesis (especially heart development) in zebrafish.
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Tai MontgomeryTai Montgomery
Associate Professor (Biology)
Small non – coding RNAs and their roles in heterochromatin formation, transcriptional elongation, translation of mRNAs, and sorting of RNAs within a cell.

Erin NishimuraErin Nishimura
Assistant Professor (Biochemistry & Molecular Biology)
Regulation of gene expression during  C. elegans embryogenesis and how it impacts cell fate.

Anireddy ReddyAnireddy S.N. Reddy
Professor (Biology)
Signal transduction mechanisms; regulation of gene expression; crop improvement by genetic engineering.
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Tom SantangeloTom Santangelo
Associate Professor (Biochemistry and Molecular Biology)
Mechanisms and regulation of archaeal transcription and RNA editing.
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Carol Wilusz HeadshotCarol Wilusz
Professor (Microbiology, Immunology & Pathology)
Post – transcriptional control of gene expression in myotonic dystrophy and stem cells.

Jeffrey WiluszJeff Wilusz
Professor (Microbiology, Immunology & Pathology)
Interactions between viruses, viral RNAs and the cellular mRNA decay machinery.

Tingting Yao HeadshotTingting Yao
Associate Professor (Biochemistry & Molecular Biology)
Regulation of gene expression and chromatin dynamics by the ubiquitin – proteasome pathway.

Affiliate Faculty

Asa Ben-Hur
Professor (Computer Science)
Machine learning for predicting protein function and alternative splicing.

Jeff Hansen
Professor (Biochemistry & Molecular Biology)
Higher order chromatin structure and chromatin architectural proteins.

Brian Munsky
Assistant Professor (Chemical & Biological Engineering)
Integrating models & experiments to understand, predict and control stochastic processes such as gene expression

Ashok Prasad
Associate Professor (Chemical & Biological Engineering)
Mathematical and computational modeling of signal transduction, gene transcription and stochastic processes in biology.

Laurie Stargell
Professor (Biochemistry & Molecular Biology)
RNA polymerase II transcription and chromatin context in S. cerevisiae.

Tim Stasevich
Assistant Professor (Biochemistry & Molecular Biology)
Live cell imaging of gene expression, especially post – translational modifications to chromatin

Coursework

  • BC 563 – Molecular Genetics
  • MIP 643 – RNA Biology
  • DSCI 510 – Linux as a computational platform
  • DSCI 511 – Genomics Data Analysis in Python
  • DSCI 512 – RNA-seq Data Analysis
  • MIP 565 / BZ 565 – Next Generation Sequencing Platforms & Libraries
  • MIP 611 – Advanced Microbiological Research Methods

Facilities & Resources

CMB Students

Hannah BerryHannah Berry (Argueso Lab)
USDA – NIFA Pre – doctoral Fellow
2019-20 Sustainability Fellow
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Katy McIntyreKaty McIntyre (Argueso Lab)
NSF – GRFP Fellow
USDA-NIFA Predoctoral Fellowship-2020
American Society of Plant Biologists Travel Award-2020

Paige Ostwald HeadshotPaige Ostwald (Garrity Lab)
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Vice President for Research Graduate Fellows Program, 2020-21 Cohort

Kailee Reed HeadshotKailee Reed (Montgomery Lab)
qCMB T32 Fellow 2019 – 20
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Kristin Scott HeadshotKristin Scott (Santangelo Lab)
GAANN Teaching Fellow 2018 – 19
qCMB T32 Fellow 2019 – 20
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Alumni

Neha AhujaNeha Ahuja (Garrity Lab)
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Adam Heck HeadshotAdam Heck (C. Wilusz Lab)
NSF – NRT GAUSSI Fellow 2015 – 16
NSF – GRFP Fellow 2016 – 19
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Nikki HuynhNikki Huynh (Reddy Lab)
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Josh SvendsenJosh Svendsen (Montgomery Lab)
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Sere Williams (MS 2019, Reddy Lab) – CMB PhD Student

Kristen Brown (PhD 2019, Montgomery Lab) – Data Science Fellow, Insight Data Science

Rasha Alnefaie (PhD 2018, Garrity Lab) – Lecturer, Albaha University

Aimee Jalkanen (PhD 2017, C. Wilusz Lab) – Clinical Research Manager, Merck

Annie Zhang Bargsten (PhD 2017, C. Wilusz Lab) – Scientific Support Specialist, Horizon Discovery

Mohammed Albaqami (PhD 2017, Reddy Lab) – Assistant Professor, Umm Al – Qura University